Severe Burn

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Management of Severe Burn Microstomia

Figure 1. Bilateral oral commissure contractures and resulting microstomia 7 months postburn. Interlabial distance 5 mm.

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Endothelin-1 levels in severe burn injuries.

HYPOTHESIS Most investigators have reported high levels of endothelin (ET)-1 in patients with thermal injury. We attempted to examine the hypothesis that ET-1 levels increase in patients with severe burn injury. PATIENTS AND METHODS Plasma from 28 adult subjects, 14 of whom had thermal injuries with a median (range) percentage of total burn surface area of 22% (20%-76%), was assessed for ET-1...

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Myocardial Autophagy after Severe Burn in Rats

BACKGROUND Autophagy plays a major role in myocardial ischemia and hypoxia injury. The present study investigated the effects of autophagy on cardiac dysfunction in rats after severe burn. METHODS Protein expression of the autophagy markers LC3 and Beclin 1 were determined at 0, 1, 3, 6, and 12 h post-burn in Sprague Dawley rats subjected to 30% total body surface area 3rd degree burns. Autop...

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Severe esophageal burn after transesophageal pacing.

3−week history of fatigue and headaches was admitted with suspected myocardi− tis. Echocardiography showed a dilated left ventricle with a shortening fraction of 12%. Electrocardiography revealed ec− topic atrial tachycardia, with a heart rate of 200 beats per minute. Cardioversion was performed to terminate the tachycar− dia, but this was unsuccessful. Intrave− nous amiodarone was started, but...

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Plasma chromogranin A after severe burn trauma

BACKGROUND Chromogranin A (CgA) in plasma (P-CgA), a neuroendocrine marker of sympathetic stress, has been shown to predict mortality in medical intensive care. We hypothesized that the magnitude of CgA release would reflect stress load, and thereby injury severity in burn intensive care patients. METHODS Fifty-one consecutive patients with a burn area exceeding 10% were included. P-CgA was m...

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ژورنال

عنوان ژورنال: The American Journal of the Medical Sciences

سال: 1861

ISSN: 0002-9629

DOI: 10.1097/00000441-186101000-00028